Cas No. | 1132661-86-9 |
别名 | 雷米普利 d5 |
Canonical SMILES | O=C([C@H](C)N[C@H](C(OCC)=O)CCC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])N2[C@]3([H])[C@](CCC3)([H])C[C@H]2C(O)=O |
分子式 | C23H27D5N2O5 |
分子量 | 421.5 |
溶解度 | Chloroform: Slightly Soluble,Methanol: Slightly Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Ramipril-d5 is intended for use as an internal standard for the quantification of ramipril by GC- or LC-MS. Ramipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor ramiprilat . Ramipril (2.5 mg/kg per day, p.o.) reduces systolic blood pressure in spontaneously hypertensive rats. It reduces aortic valve backscatter and improves aortic flow in a rabbit model of aortic valve stenosis. Ramipril also decreases paw swelling and serum levels of TNF-α and prostaglandin E2 (PGE2) as well as cardiac collagen deposition and fibrosis in a rat model of adjuvant-induced arthritis. |