Cas9-IN-1

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Cas9-IN-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

产品介绍

Cas9-IN-1是一种有效的Cas9抑制剂 (IC₅₀=7.02 μM)，通过与 apo-Cas9 结合防止 Cas9:gRNA 复合物形成来发挥作用。

生物活性	Cas9-IN-1 is a potentCas9inhibitor (IC₅₀=7.02 μM), acting by binding to apo-Cas9 to prevent Cas9:gRNA complex formation^[1].
体外研究 (In Vitro)	Cas9-IN-1 (compound 85) (5 and 13 μM; overnight) can detach gRNA from preformed Cas9:gRNA complex while having weaker inhibitory activity, helping theE. coliselection strain to survive SpyCas9-induced killing^[1].
分子量	451.25
Formula	C₁₇H₁₁Cl₂F₃N₂O₃S
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.