CAS NO: | 1450833-55-2 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
CAS: | 1450833-55-2 |
分子式: | C19H20F3N5O5S2 |
分子量: | 519.52 |
纯度: | >98% |
溶解性: | DMSO : 50 mg/mL (96.24 mM; Need ultrasonic); H2O : 1 mg/mL (1.92 mM; Need ultrasonic) |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cancer |
Target: | IC50: 1 nM (UBA1) |
描述: | TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global |