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Cicloprofen
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cicloprofen图片
CAS NO:36950-96-6
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
250mg电议

产品介绍
An NSAID
Cas No.36950-96-6
别名环洛芬
Canonical SMILESO=C(C(C)C1=CC=C2C3=C(CC2=C1)C=CC=C3)O
分子式C16H14O2
分子量238.3
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 20 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cicloprofen is a non-steroidal anti-inflammatory drug (NSAID).1,2It inhibits histamine release induced by ragweed, A23187 , or concanavalin A in isolated human leukocytes when used at a concentration of 0.5 mM.1Cicloprofen inhibits carrageenan-induced paw edema in rats (ED50= 67 mg/kg).2

1.Hearn, T., and Wojnar, R.J.Characterization of augmentation of allergic and non-allergic histamine release by non-steroidal anti-inflammatory/analgesic agentsAgents Actions11(4)352-360(1981) 2.Stiller, E.T., Diassi, P.A., Gerschutz, D., et al.Synthesis and antiinflammatory activities of α-methylfluorene-2-acetic acid and related compoundsJ. Med. Chem.15(10)1029-1032(1972)