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HG-14-10-04
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
HG-14-10-04图片
CAS NO:1356962-34-9
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
2mg电议
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
HG-14-10-04是特异的ALK抑制剂,IC50为20 nM。
Cas No.1356962-34-9
Canonical SMILESClC1=CN=C(NC2=CC=C(N3CCC(N4CCN(C)CC4)CC3)C=C2OC)N=C1C5=CNC6=CC=CC=C65
分子式C29H34ClN7O
分子量532.08
溶解度DMSO: 13.3 mg/mL (25.00 mM and warming)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: ALKMore information can be found in the following Patent, Example 10Preparation of substituted pyrimidinamines as ALK kinase inhibitorsBy Aquila, Brian; Kamhi, Victor; Peng, Bo; Pontz, Timothy; Saeh, Jamal Carlos; Thakur, Kumar; Yang, Bin From U.S. Pat. Appl. Publ. (2012), US 20120028924 A1 20120202.

[1]. U.S. Pat. Appl. Publ. (2012), US 20120028924 A1