Heptelidic acid is an esquiterpene lactone produced by the fungus T. koningii with antibiotic activity against anaerobic bacteria such as Bacteroides. It acts as an irreversible (covalent) inhibitor of GAPDH that binds to the cysteine-149 residue at the active site of the enzyme. References: Sakai K, Hasumi K, Endo A. Two glyceraldehyde-3-phosphate dehydrogenase isozymes from the koningic acid (heptelidic acid) producer Trichoderma koningii. Eur J Biochem. 1990 Oct 5;193(1):195-202. PubMed PMID: 2226438.

纯度：≥98%

CAS：57710-57-3