Boc-NH-PEG2-CH2COOH是一种基于PEG合成的PROTAClinker，用于合成PROTAC。
货号:ajcx30296
CAS:108466-89-3
分子式:C11H21NO6
分子量：263.29
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020 Feb 1;187:111952.