包装: | 1mg |
规格: | 98% |
市场价: | 3837元 |
分子量: | 457.5 |
Background:
K252d is an indolocarbazole alkaloid found inNocardiopsis.1It is a PKC inhibitor that inhibits PKC isolated from rat brain (IC50= 350 nM). It also inhibits calcium- and calmodulin-dependent phosphodiesterase isolated from bovine heart (IC50= 46.2 µM).
1.Nakanishi, S., Matsuda, Y., Iwahashi, K., et al.K-252b, c and d, potent inhibitors of protein kinase C from microbial originJ. Antibiot. (Tokyo) 39(8)1066-1071(1986)