规格: | 98% |
分子量: | 216.2 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Background:
(S)-O-Desmethyl naproxen is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen; It is formed from (S)-naproxen by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.
1.Miners, J.O., Soulter, S., Tukey, R.H., et al.Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxenBiochem. Pharmacol.51(8)1003-1008(1996)