MAL2-11B (116-9e) is a novel and potent inhibitor of Simian Virus 40 replication by acting as a blocker of Hsp40-Hsp70 binding thereby inhibiting the chaperone activity of Hsp70-Hsp40. It works by targeting the molecular chaperone function and ATPase activity of T antigen. MAL2-11B is also a MAL3-101 precursor.