CAS NO: | 129318-43-0 |
规格: | 98% |
分子量: | 271.08 |
包装 | 价格(元) |
500mg | 电议 |
1g | 电议 |
Background:
Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS); causes macrophage apoptosis. Inhibits prenylation and sterol biosynthesis in purified osteoclasts.