WS-12 是有效的TRPM8激动剂，EC50为 39 nM。

WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)

WS-12, had an EC(50) value about 2000 times lower than that of menthol and is, therefore, the highest-affinity TRPM8 ligand known to date.

68489-09-8

C18H27NO2

289.419

DMSO:20 mg/mL (69.11 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years