Balsalazide sodium hydrate 可通过调节IL-6/STAT3通路起抑癌作用,可用于治疗炎症性肠病。
产品描述
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug. High dose balsalazide (3.0 g twice daily) was superior in maintaining remission in patients with ulcerative colitis compared with a low dose (1.5 g twice daily) or a standard dose of mesalazine (0.5 g three times daily). All three treatments were safe and well tolerated [1]. Balsalazide is approved for the treatment of mild-to-moderate active UC. It is efficacious for the induction of remission in mild to moderate UC and has a favorable safety profile, with the added advantages of greater efficacy of remission induction and rapidity of onset [2].
Cas No.
150399-21-6
分子式
C17H17N3Na2O8
分子量
437.316
别名
Balsalazide disodium;Balsalazide disodium dihydrate;巴柳氮钠;巴柳氮钠水合物;Balsalazide disodium salt dihydrate
储存和溶解度
DMSO:198.9 mM
H2O:198.9 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years