TLR4-IN-C34 是 TLR4 的抑制剂,可减少内毒素血症和坏死性小肠结肠炎模型中的全身炎症
产品描述
TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis
体外活性
TLR4-IN-C34 reduced systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.
动物实验
Experimental NEC was induced in 7 8 day old mice .TLR4-IN-C34 was administered via the oral route at a concentration of 1 mg/kg on each morning of the four day model.
Cas No.
40592-88-9
分子式
C17H27NO9
分子量
389.4
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years