Vindoline 是一种从长春花叶子中提取的长春花生物碱,对微管蛋白自组装具有微弱的抑制作用。
Cas No. | 2182-14-1 |
别名 | 文多灵 |
化学名 | (3a1R,4R,5S,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate |
Canonical SMILES | O=C([C@@]1([C@]2([H])N(C([H])([H])[H])C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])[C@]24[C@@](C(C([H])([H])C([H])([H])[H])(C([H])=C([H])C5([H])[H])[C@@]1([H])OC(C([H])([H])[H])=O)([H])N5C([H])([H])C4([H])[H])O[H])OC([H])([H])[H] |
分子式 | C25H32N2O6 |
分子量 | 456.53 |
溶解度 | ≥ 45.7mg/mL in DMSO |
储存条件 | 4°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Vindoline is a monomeric vinca-alkaloid,forms lower portion of the lead anti-tumor agents,vinblastine and vincristine. Vindoline exhibits reciprocal cross-resistance to vincristine and vinblastine. |