CAS NO: | 2097125-54-5 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
生物活性 | Garetosmab (REGN 2477) is a fully humanIgG4monoclonal antibody that specifically inhibitsactivin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research[1]. |
体外研究 (In Vitro) | Garetosmab (REGN 2477) specifically binds to and blocks signaling of activin proteins containing the inhibin βα subunit (activins A, AB, and AC). In vitro, Garetosmab has high affinity and specificity for activins A, AB, and AC, but does not bind or functionally inhibit other TGF-β family ligands that share the same activin receptor pathways, including activin B, inhibin A, BMP-2, BMP6, BMP9, BMP10, GDF8, and GDF11[1]. |
CAS 号 | 2097125-54-5 |
中文名称 | 加托索单抗 |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |