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PTACH

品牌
J&K
CAS
848354-66-5
货号
786110
规格纯度
98%, 一种新型HDAC抑制剂, 有效抑制各种人癌细胞生长
参考价格
760 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
848354-66-5
PTACH
NCH-51
产品介绍:

基本信息

分子式C20H26N2O2S2
分子量390.56
存储条件Freezer -20℃

产品描述

PTACH (NCH-51) is a SAHA-based novel inhibitor of human HDAC. PTACH exerts potent growth inhibition against various human cancer cells, with EC50 values ranging from 1 to 10 μM. IC50 value: 1-10 μM (EC50) Target: HDAC in vitro: In cancer cell growth inhibition assay, PTACH shows strong activity. PTACH inhibits various cancer cells with EC50 of 2.3, 9.1, 3.0, 2.6, 1.1, 4.5, 2.4, 5.0, and 4.5 μM for MDA-MB-231 breast cancer, SNB-78 central nervous system, HCT116 colon cancer, NCI-H226 lung cancer, LOX-IMVI melanoma, SK-OV-3 ovarian cancer, RXF-631L renal cancer, St-4 stomach cancer, and DU-145 prostate cancer.

靶点(IC50 & Targe)

HDAC

参考文献

[1]. Suzuki T, et al. Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates. J Med Chem. 2005 Feb 24;48(4):1019-1032.

安全信息

图形或危害标志
提示语Danger
危险说明H318
H413
防范说明P273
P280
P305+P351+P338
P310
P501

百灵威科技

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