蛋白质/抗原/多肽 >> 重组蛋白
重组味觉受体蛋白家族2亚基60
产品介绍 基因名: TAS2R60 产品别名: T2R56; T2R60; TAS2R60; taste 2 receptor member 60; taste 2 receptor member 60; taste receptor type 2 member 60; taste receptor type 2 member 56; taste receptor, type 2, member 60; 味觉受体蛋白家族2亚基60; 背景信息: T2R60 is a 318 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. T2R60 acts as a receptor that may play a role in the perception of bitterness, and is also thought to be involved in sensing the chemical composition of gastrointestinal content. As a gustducin-linked receptor, the activity of T2R60 may stimulate G alpha (alpha gustducin), mediate PLC beta 2 activation and lead to the gating of TRPM5. While expressed in subsets of taste receptor cells of the tongue and palate epithelium, T2R60 is found exclusively in gustducin-positive cells. The gene that encodes T2R60 contains 957 bases and maps to human chromosome 7q35. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. 标签:His-tag |
相关产品
|