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蛋白质/抗原/多肽 >> 重组蛋白
重组毛皮质细胞角蛋白/细胞角蛋白40
重组毛皮质细胞角蛋白/细胞角蛋白40图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:重组角蛋白40(KRT40)
Recombinant KRT40
产品介绍
基因名:

KRT40


产品别名:

CK-40; K40; KA36; KRT40; keratin 40; keratin 40; keratin, type I cytoskeletal 40; cytokeratin-40; keratin 40, type I; type I hair keratin KA36; 毛皮质细胞角蛋白/细胞角蛋白40; 角蛋白40(KRT40);


背景信息:
Keratin 40 (KRT40), also known as Cytokeratin-40 (CK-40) or KA36, is a 431 amino acid protein that belongs to the intermediate filament family. As a heterotetramer of two type I and two type II keratins, Keratin 40 may play a role in late hair differentiation. While weakly expressed in tongue, breast, colon and small intestine, Keratin 40 is highly expressed in skin and scalp. The gene that encodes Keratin 40 consists of approximately 9,420 bases and maps to human chromosome 17q21.2. Encoding more than 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of ovary, colon, prostate gland and fallopian tubes.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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