蛋白质/抗原/多肽 >> 重组蛋白
重组CENTG3蛋白
产品介绍 基因名: AGAP3 产品别名: AGAP-3; CENTG3; CRAG; MRIP-1; cnt-g3; AGAP3; ArfGAP with GTPase domain, ankyrin repeat and PH domain 3; ArfGAP with GTPase domain, ankyrin repeat and PH domain 3; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3; CRAM-associated GTPase; CRMP (collapsin response mediator protein) associated; MR1-interacting protein; centaurin-gamma-3; CENTG3蛋白; 背景信息: ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. These proteins are best characterized as regulators of membrane traffic. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of Arf-dependent pathways. This family includes ASAP1, ACAP1, ACAP2, AGAP1, ARAP1, ARAP2, Centaurin a1 and Centaurin g3. The Centaurin a1 protein is a high affinity PtdIns(3,4,5)P3 binding protein enriched in brain. By acting as a GTPase activating protein for ADP ribosylation factor 6 (ARF6), Centaurin a1 is able to switch off ARF6 and inhibit its ability to mediate b2-adrenoceptor internalization and negatively regulate ARF6 activity by functioning as an in vivo PIP3 dependent ARF6 GAP OTTHUMP00000213337; domain, five PH domains, one Ras-associating domain, one Rho-GAP domain and one SAM (sterile a motif) domain. 标签:His-tag |
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