蛋白质/抗原/多肽 >> 重组蛋白
重组Rho GTP酶激活蛋白24
产品介绍 基因名： ARHGAP24 产品别名： FILGAP； RC-GAP72； RCGAP72； p73； p73RhoGAP； ARHGAP24； Rho GTPase activating protein 24； Rho GTPase activating protein 24； rho GTPase-activating protein 24； RAC1- and CDC42-specific GTPase-activating protein of 72 kDa； filamin-A-associated RhoGAP； rhoGAP of 73 kDa； sarcoma antigen NY-SAR-88； Rho GTP酶激活蛋白24； 背景信息： ARHGAP24 is a rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. It acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. It controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. There are five different isoforms.Isoform 1 is widely expressed with a higher level in kidney. Isoform 2 is mainly expressed in endothelial cells and is involved in modulation of angiogenesis. 标签：His-tag |
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