蛋白质/抗原/多肽 >> 重组蛋白
重组活化转录因子72蛋白
产品介绍 基因名: Atf7ip2 产品别名: 4930558K11Rik; BC018510; Get-1; PSM2; Atf7ip2; activating transcription factor 7 interacting protein 2; activating transcription factor 7 interacting protein 2; activating transcription factor 7-interacting protein 2; MBD1-containing chromatin-associated factor 2; protein similar to MCAF2; 活化转录因子72; 背景信息: MCAF2 is a 682 amino acid nuclear protein that exists as two alternatively spliced isoforms. MCAF2 can act as either an activator or repressor, thereby modulating chromatin formation and/or transcription regulation by linking transcription factors to transcription apparatuses. A member of the MCAF family, MCAF2 contains one fibronectin type-III domain and is thought to form a complex with ESET and MBD1. The gene encoding MCAF2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. 标签:His-tag |
相关产品
|