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蛋白质/抗原/多肽 >> 重组蛋白
重组CMBL蛋白
重组CMBL蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant Cmbl
Recombinant carboxymethylenebutenolidase-like (Pseudomonas) protein
产品介绍
基因名:

Cmbl


产品别名:

2310016A09Rik; Cmbl; carboxymethylenebutenolidase-like (Pseudomonas); carboxymethylenebutenolidase-like (Pseudomonas); carboxymethylenebutenolidase homolog; CMBL蛋白;


背景信息:
CMBL is a 245 amino acid cytosolic protein and cysteine hydrolase that preferentially cleaves cyclic esters. A member of the dienelactone hydrolase family, CMBL is the human homolog of Pseudomonas dienelactone hydrolase, a protein that participates in the bacterial halocatechol degradation pathway. CMBL is ubiquitously expressed with high expression in liver, colon, kidney and small intestine, where it acts as a bioactivating enzyme for a prodrug type angiotensin II type 1 receptor antagonist known as olmesartan medoxomil. CMBL is inhibited by p-chloromercuribenzoate (PCMB) and is encoded by a gene that maps to human chromosome 5p15.2. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm, or of chromosome 5 altogether, is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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