蛋白质/抗原/多肽 >> 重组蛋白
重组6号染色体开放阅读框173蛋白
产品介绍 基因名: Cenpw 产品别名: 2610036L11Rik; Cug2; Cenpw; centromere protein W; centromere protein W; centromere protein W; CENP-W; cancer-up-regulated gene 2 protein; 6号染色体开放阅读框173; 背景信息: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPW has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis. 标签:His-tag |
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