产品介绍 基因名： SLCO1C1 产品别名： OATP-F； OATP1； OATP14； OATP1C1； OATPF； OATPRP5； SLC21A14； SLCO1C1； solute carrier organic anion transporter family member 1C1； solute carrier organic anion transporter family member 1C1； solute carrier organic anion transporter family member 1C1； OAT-RP-5； OATP-14； organic anion transporter F； organic anion transporter polypeptide-related protein 5； organic anion transporting polypeptide 14； solute carrier family 21 (organic anion transporter), member 14； solute carrier family 21 member 14； thyroxine transporter； 溶质载体家族蛋白21成员1C1； 背景信息： The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. OATP-F is a 712 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, OATP-F mediates the Na+-independent, high affinity transport of the thyroid hormones thyroxine (T4) and rT3 and other organic anions. OATP-F is also thought to transport estrone-3-sulfate and sulfobromophthalein (BSP), triiodothyronine (T3) and 17-beta-glucuronosyl estradiol at a much lower efficiency. OATP-F is expressed highly in Leydig cells in testis and in brain. 标签：His-tag |
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