蛋白质/抗原/多肽 >> 重组蛋白
重组hUPF2蛋白
产品介绍 基因名： UPF2 产品别名： HUPF2； RENT2； smg-3； UPF2； UPF2 regulator of nonsense mediated mRNA decay； UPF2 regulator of nonsense mediated mRNA decay； regulator of nonsense transcripts 2； FRS2/UPF2/LEMD3 fusion； LEMD3/UPF2 fusion； UPF2 regulator of nonsense transcripts homolog； nonsense mRNA reducing factor 2； smg-3 homolog, nonsense mediated mRNA decay factor； up-frameshift suppressor 2 homolog； yeast Upf2p homolog； hUPF2蛋白； 背景信息： This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq, Jul 2008] 标签：His-tag |
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