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蛋白质/抗原/多肽 >> 重组蛋白
重组含Kelch域蛋白2(KLHDC2)
重组含Kelch域蛋白2(KLHDC2)图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:重组肝癌相关抗原33蛋白
Recombinant KLHDC2
产品介绍
基因名:

KLHDC2


产品别名:

HCLP-1; HCLP1; LCP; KLHDC2; kelch domain containing 2; kelch domain containing 2; kelch domain-containing protein 2; hepatocellular carcinoma-associated antigen 33; host cell factor homolog LCP; host cell factor-like protein 1; 含Kelch域蛋白2(KLHDC2); 肝癌相关抗原33;


背景信息:
KLHDC2 is a 406 amino acid protein that contains six kelch repeats. Localizing to the nucleus, KLHDC2 is widely expressed, with high levels found in muscle, heart, pancreas and liver. KLHDC2 interacts directly with CREB3, repressing CREB3-mediated transcription. Existing as two alternatively spliced isoforms, the gene encoding KLHDC2 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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