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蛋白质/抗原/多肽 >> 重组蛋白
重组活化T细胞核因子胞浆2蛋白
重组活化T细胞核因子胞浆2蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Recombinant Nfatc2ip
Recombinant nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
产品介绍
基因名:

Nfatc2ip


产品别名:

D7Ertd304e; NIP45; Nfatc2ip; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein; NFATC2-interacting protein; 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; nuclear factor of activated T-cells, cytoplasmic 2-interacting protein; 活化T细胞核因子胞浆2;


背景信息:
NFATc2IP is a 419 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one ubiquitin-like domain. Interacting with NFATc2, TRAF1 and TRAF2, NFATc2IP plays a role in the inducible expression of cytokines in T-cells, specifically by enhancing NFATc2-induced interleukin (IL) production. NFATc2IP exists as three alternatively spliced isoforms and is subject to post-translational methylation; an event which augments NFATc2IP-regulated cytokine production. The gene encoding NFATc2IP maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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