产品介绍 基因名： APOBEC3B 产品别名： A3B； APOBEC1L； ARCD3； ARP4； DJ742C19.2； PHRBNL； bK150C2.2； APOBEC3B； apolipoprotein B mRNA editing enzyme catalytic subunit 3B； apolipoprotein B mRNA editing enzyme catalytic subunit 3B； DNA dC->dU-editing enzyme APOBEC-3B； apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B； cytidine deaminase； phorbolin 2； phorbolin 3； phorbolin-1-related protein； phorbolin-2/3； probable DNA dC->dU-editing enzyme APOBEC-3B； 载脂蛋白B-mRNA编辑酶复合物3B； 背景信息： APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. APOBEC3 proteins are thought to be RNA editing enzymes and have roles in cell growth. APOBEC3B, also known as phorbolin-1-related protein or phorbolin-2/3, is a 382 amino acid protein belonging to the cytidine and deoxycytidylate deaminase family. APOBEC3B lacks cytidine deaminase activity on RNA molecules, but has been shown to bind to apoB and AU-rich RNAs. APOBEC3B forms a homodimer and interacts with APOBEC3G. APOBEC3B is expressed at at moderate levels in heart, testis, thymus, prostate, ovary, spleen and peripheral blood leukocytes. 标签：His-tag |
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