重组环指蛋白105

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重组环指蛋白105


交货期:	1周
产品别名:	Recombinant TTC3 Recombinant tetratricopeptide repeat domain 3 protein

产品介绍

基因名：

TTC3

产品别名：

DCRR1； RNF105； TPRDIII； TTC3； tetratricopeptide repeat domain 3； tetratricopeptide repeat domain 3； E3 ubiquitin-protein ligase TTC3； RING finger protein 105； RING-type E3 ubiquitin transferase TTC3； TPR repeat protein 3； TPR repeat protein D； tetratricopeptide repeat protein 3；环指蛋白105；

背景信息：

E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。