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钾离子通道多聚体结构域蛋白21抗体
钾离子通道多聚体结构域蛋白21抗体图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Anti-KCTD21
Anti-potassium channel tetramerization domain containing 21 Antibody
产品介绍
靶标:

KCTD21


产品别名:

KCASH2; KCTD21; potassium channel tetramerization domain containing 21; potassium channel tetramerization domain containing 21; BTB/POZ domain-containing protein KCTD21; potassium channel tetramerisation domain containing 21; potassium channel tetramerization domain-containing protein 21; 钾离子通道多聚体结构域蛋白21;


背景信息:
Swiss-Prot Acc.Q4G0X4.Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142).

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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