Rab7b抗体

抗体 >> 其他抗体

Rab7b抗体


交货期:	1周
产品别名:	Anti-Rab7b Anti-RAB7B, member RAS oncogene family Antibody

产品介绍

靶标：

Rab7b

产品别名：

5430435G22Rik； Rab7b； RAB7B, member RAS oncogene family； RAB7B, member RAS oncogene family； ras-related protein Rab-7b；

背景信息：

Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN. Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。