产品介绍 靶标： ATP6V1G3 产品别名： ATP6G3； Vma10； ATP6V1G3； ATPase H+ transporting V1 subunit G3； ATPase H+ transporting V1 subunit G3； V-type proton ATPase subunit G 3； ATPase, H+ transporting, lysosomal (vacuolar proton pump) subunit G3； ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3； V-ATPase 13 kDa subunit 3； V-ATPase G subunit 3； V-ATPase G3 subunit； V-ATPase subunit G 3； vacuolar ATP synthase subunit G 3； vacuolar proton pump G subunit 3； vacuolar proton pump subunit G 3； vacuolar proton pump, subunit G3； 背景信息： This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding 宿主：Rbt |
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