产品介绍 靶标： PLEKHM2 产品别名： SKIP； PLEKHM2； pleckstrin homology and RUN domain containing M2； pleckstrin homology and RUN domain containing M2； pleckstrin homology domain-containing family M member 2； PH domain-containing family M member 2； SifA (Salmonella-induced filaments A) and kinesin-interacting protein； novel RUN and PH domain-containing protein； pleckstrin homology domain containing, family M (with RUN domain) member 2； 血小板白细胞C激酶底物同源结构域M2； 背景信息： PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo. 宿主：Rbt |
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