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SMPDL3A抗体
SMPDL3A抗体图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:Anti-SMPDL3A
Anti-sphingomyelin phosphodiesterase acid like 3A Antibody
产品介绍
靶标:

SMPDL3A


产品别名:

ASM3A; ASML3a; yR36GH4.1; SMPDL3A; sphingomyelin phosphodiesterase acid like 3A; sphingomyelin phosphodiesterase acid like 3A; acid sphingomyelinase-like phosphodiesterase 3a; 0610010C24Rik; ASM-like phosphodiesterase 3a;


背景信息:
SMPDL3A gene is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. LXR α and LXRβ function as physiological sensors of cholesterol metabolites (oxysterols), regulating key genes involved in cholesterol and lipid metabolism. LXRs have been extensively studied in both human and rodent cell systems, revealing their potential therapeutic value in the contexts of atherosclerosis and inflammatory diseases. The LXR genome landscape has been investigated in murine macrophages but not in human THP-1 cells, which represent one of the frequently used monocyte/macrophage cell systems to study immune responses.

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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