产品介绍 靶标: PTPRU 产品别名: FMI; PCP-2; PTP; PTP-J; PTP-PI; PTP-RO; PTPPSI; PTPRO; PTPU2; R-PTP-PSI; R-PTP-U; hPTP-J; PTPRU; protein tyrosine phosphatase receptor type U; protein tyrosine phosphatase receptor type U; receptor-type tyrosine-protein phosphatase U; PTP pi; Receptor protein tyrosine phosphatase hPTP-J; pancreatic carcinoma phosphatase 2; pi R-PTP-Psi; protein-tyrosine phosphatase J; protein-tyrosine phosphatase pi; protein-tyrosine phosphatase receptor omicron; receptor-type protein-tyrosine phosphatase psi; 蛋白酪氨酸磷酸酶受体U(PTPRU); 背景信息: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced trans 宿主:Rbt |
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