产品介绍 靶标： SLC19A1 产品别名： CHMD； FOLT； IFC-1； IFC1； MEGAF； REFC； RFC； RFC1； RFT-1； hRFC； hSLC19A1； SLC19A1； solute carrier family 19 member 1； solute carrier family 19 member 1； reduced folate transporter； folate transporter 1； intestinal folate carrier 1； placental folate transporter； reduced folate carrier 1； reduced folate carrier protein； reduced folate transporter 1； solute carrier family 19 (folate transporter), member 1； 叶酸转运蛋白(FOLT)； 溶质载体家族蛋白19成员A1； 背景信息： Solute carrier family 19 (folate transporter), member 1, also known as SLC19A1 or RFC1, is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. And RFC1 plays a role in maintaining intracellular concentrations of folate. 宿主：Rbt |
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