型号: | recombinant, expressed in E. coli, lyophilized powder |
货号: | 465287 |
品牌: | Sigma |
纯度含量: | ≥98% (SDS-PAGE) |
产品别名: | 磷酸二酯酶 3':5'-环核苷酸活化剂 Calmodulin bovine CaM, Phosphodiesterase 3:5-cyclic nucleotide activator Phosphodiesterase 3':5'-cyclic nucleotide activator |
基本信息:
MDL编号(化学反应和变化识别号)【MDL number】 : MFCD00131869
备注【Preparation Note】 : Produced using animal component-free materials.
生物化学/生理学作用【Biochem/physiol Actions】 : Ca2+ binding protein that is required for activation of cyclic nucleotide-dependent phosphodiesterase. It is also a cofactor/activator of nitric oxide synthase, calcineurin, and many kinases including ATPase, myosin light chain kinase, and CAM kinase I, II, and III. It mediates ryanodine receptor activation by cyclic ADP-ribose and is involved in intracellular Ca2+ homeostasis.
物理性质【Physical properties】 : Sequence:
MGSSHHHHHHSSGLVPRGSHMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
重组体【recombinant】 : expressed in E. coli
形态【form】 : lyophilized powder
分子量【mol wt】 : Mw 19000.9 by amino acid sequence
组成【composition】 : Protein, ≥85%
存储温度【storage temp.】 : -20℃
安全信息:
德国水质危险性分类【WGK Germany】 : 3