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BRAF(G469E)小鼠单抗
BRAF(G469E)小鼠单抗图片
型号:BRAF(G469E)
货号:26196
品牌:NewEast Biosciences
参考价格:4800元/个
包装:100微升
交货期:现货


包装与价格:
订货号纯度规格包装价格(元)
26196100微升4800
产品名称
Anti BRAF(G469E) Mouse Monoclonal Antibody
产品介绍
描述:   Anti-BRAF(G469E) Mouse Monoclonal Antibody
背景介绍:    BRAF belongs to a family of serine-threonine protein kinases. As a part of a signaling pathway known as the the RAS/MAPK pathway, it plays an important part in many cellular processes. The processes include cell proliferation, differentiation and transcriptional regulation. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been found in cancers.
免疫原:   A synthetic peptide from the internal region of BRAF , which includes the mutation of G469E, human origin
经过测试的应用:   ELISA, WB, IHC


种属反应性:   Recognizes G469E mutant, but not wild-type BRAF of vertebrates
储存条件:    Store at -20°C. Avoid repeated freezing and thawing

蛋白质印迹:   

Western blot analysis of recombinant BRAF (G469E) and wildtype proteins.

Purified His-tagged BRAF (G469E) protein (lane 2) and corresponding wildtype protein (lane 1) were blotted with Anti-BRAF(G469E) monoclonal antibody (cat. # 26196).

免疫荧光:   

Immunofluorescence of cells expressing BRAF proteins with Anti-BRAF(G469E) antibody.

HEK293T cells were transfected with pCDNA3-GFP-BRAF (WT) plasmid (left column) or pCDNA3-GFP-BRAF (G469E) plasmid (right column), then fixed and stained with Anti-BRAF(G469E) monoclonal antibody (cat. # 26196).


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