糖蛋白V(CD42d)抗体
产品名称 Anti-GP5 Anti-glycoprotein V platelet Antibody 产品介绍
靶标: GP5 产品别名: CD42d; GPV; GP5; glycoprotein V platelet; glycoprotein V platelet; platelet glycoprotein V; glycoprotein 5; 糖蛋白Ⅴ(CD42d); 背景信息: Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010], 宿主:Rbt 用户评论 产品评分 目前评分共0人 产品质量
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