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CAS: 51-83-2
分子式: C6H15ClN2O2
分子量: 182.65
熔点: 200-204℃
中文名称: 
卡巴胆碱
氨甲酰胆碱
氨甲酰胆碱盐酸盐
卡巴可
氯化铵甲酰胆碱
英文名称: 
karbachol
carcholin
choline carbamate chloride
choline, chloride, carbamate
coletyl
doryl
doryl (pharmaceutical)
2-((aminocarbonyl)oxy)-n,n,n,-trimethyl-ethanaminiu chloride
2-(aminocarbonyl)oxy-n,n,n-trimethyl-ethanaminiu chloride
2-[(aminocarbonyl)oxy]-n,n,n-trimethyl-ethanaminiu chloride
gamma-carbamoyl choline chloride
jestryl
carbyl
karbamoylcholin chlorid
lentin
lentine
lentine (french)
miostat
moryl
tl 457
vasoperif
2-[(Aminocarbonyl)oxy]-N,N,N-trimethyle-thanaminium chloride
carbacholchloride
carbacolina
(2-hydroxyethyl)trimethyl ammonium chloride carbamate
2-((aminocarbonyl)oxy)-n,n,n-trimethylethanaminium chloride
2-((aminocarbonyl)oxy)-n,n,n-trimethylethanaminum chloride
carbach
carbachol
carbachol chloride
carbacholin
carbacholine
carbacholine chloride
carbacholum
carbacholum chloratum
(2-carbamoyloxyethyl)trimethylammonium chloride
carbamic acid, ester with choline chloride
carbaminocholine chloride
carbaminoylcholine chloride
carbamiotin
carbamoylcholine chloride
carbamoylcholine-hydrochloride
carbamylcholine chloride
carbochol
carbocholin
carbocholine
性质描述: 棱形结晶。熔点204-205℃。每克该品能溶于1ml水,50ml乙醇,10ml甲醇;几乎不溶于氯仿、乙醚,水溶液呈中性。有吸湿性,有微弱的脂肪胺类气味。
生产方法: 以β-氯乙醇为原料,经光气酰化,制得氯甲酸-β-氯乙酯:然后与氨反应生成氨基甲酸-β-氯乙酯,最后与三甲胺成季铵盐反应而得卡巴胆碱:卡巴胆碱的另一种制法是采用氯化胆碱和尿素为原料:当采用配料比氯化胆碱:尿素:亚硝酸钠:硫酸=1:1:1.15:1.35,在60℃反应约40h,能以71%的收率获得得卡巴胆碱。
用途: 该品为拟胆碱药,也用作副交感神经兴奋药。作兽药时用于大动物,治疗马的急性腹痛等。小鼠口服LD50为15mg/kg,静脉注射为0.3mg/kg。
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