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CAS: 389-08-2
分子式: C12H12N2O3
分子量: 232.24
熔点: 225-231℃
中文名称: 
1-乙基-7-甲基-4-酮-1,8-萘啶-3-羧酸
1-乙基-1,4-二氢-7-甲基-4-氧代-1,8-萘啶-3-羧酸
萘啶酸
1-乙基-7-甲基-1,8-萘啶-4-酮-3-羧酸
萘啶酮酸
英文名称: 
specifen
eucisten
innoxalon
kusnarin
nalidicron
nalitucsan
nalix
nalurin
nci-c56199
neggram
negram
nicelate
nsc-82174
poleon
dixiben
specifin
uralgin
uriben
uriclar
urodixin
uroman
uroneg
uropan
1,8-Naphthyridine-3-carboxylic acid,1-ethyl-1,4-dihydro-7-methyl-4-oxo-
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
Naldixic acid
1-Ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carbox
Nogram
3-Carboxy-1-ethyl-7-methyl-1,8-naphthidin-4-one
1,4-Dihydro-1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxilic acid
1-Ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid
1-Ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Nalidic acid
Nalidixan
Nalidixic acid
Nalidixin
Nalidixinic acid
Narigix
Naxuril
Nevigramon
8-Naphthyridine-3-carboxylic acid, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1
Urisal
Win 18,320
Wintomylon
1-ethyl-1,4-dihydro-7-methyl-4-oxo-8-naphthyridine-3-carboxylic acid
1-aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure
1-ethyl-7-methyl-1,8-naphthyridin-4-one-3-carboxylic acid
3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one
acide 1-etil-7-metil-1,8-naftiridin-4-one-3-carbossilico
acide nalidixico
acide nalidixique
betaxina
cybis
性质描述: 白色至极淡黄色结晶性粉末。熔点229-230℃。23℃时的溶解度(mg/ml):氯仿35,甲苯1.6,甲醇1.3,乙醇0.9,水0.1,醚0.1。无臭,几乎无味。
生产方法: 由2-甲基吡啶制得2-氨基-5-甲基吡啶,再与原甲酸乙酯及丙二酸二乙酯缩合成N-(2-甲基-5-氨基吡啶)甲叉丙二酸二乙酯,然后将其在260-270℃环合后再加入氢氧化钠稀溶液中水解,得到7-甲基-1,8-萘啶-4-羟基-3-羟酸。最后用溴乙烷进行N-烷基化并异构成萘啶酮酸。
用途: 该品为抗菌剂,能抑制细菌DNA、RNA的合成,用于治疗革兰氏阴性细菌所致的尿道感染。萘啶酮酸是喹诺酮类的第一代抗菌药代表,第二代则以吡哌为代表。第三代喹诺酮类抗菌药物的代表是氟哌酸。
389-08-2 供应商:
公司名称:广州伟伯科技有限公司
业务QQ:2483205017
联系电话:020-36393398
联系传真:020-36393398
产品详情:389-08-2
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