CAS 36104-80-0; 卡马西泮; Dimethylcarbamic acid 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-ylester

CAS:

36104-80-0

分子式:

C19H18ClN3O3

分子量:

371.82

中文名称:

卡马西泮

氨酯安定

3-N,N-二甲氨基甲酰氧代-1-甲基-7-氯-5-苯基-1,3-二氢-2H-1,4-苯并二氮-2-酮

英文名称:

Dimethylcarbamic acid 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-ylester

7-Chloro-1,3-dihydro-3-(N,N-dimethylcar-bamoyl)-1-

dimethyl-, 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1h-1,4-carbamic aci

benzodiazepin-3-yl ester

3-n,n-dimethylcarbamoyloxy-7-chloro-5-phenyl-1-methyl-1,3-dihydro-2h-1,4 -ben

7-chloro-1,3-dihydro-3-(n,n-dimethylcarbamoyl)-1-methyl-5-phenyl-2h-1,4- benz

7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-1,4-benzodiazepin-2-one dime

thylcarbamate

albego

b 5333

camazepam

sb 5833

性质描述:

白色结晶性粉末。熔点173-174℃。溶于乙醇，尚易溶于水。

生产方法:

由7-氯-5-苯基-1-甲基-3-羟基-1，3-二氢-2H-1，4-苯并二氮杂 -2-酮经与氯甲酸苯酯缩合、与二甲胺置换而得。

用途:

用作安定药和抗抑郁药。小鼠口服LD50为970毫克/公斤，大鼠LD50大于4000毫克/公斤。